Patrick Nasmyth was born at Edinburgh, the eldest son of Alexander Nasmyth (1758 - 1840). Taught the principles of landscape painting in the Italian style by his father, he moved to London in 1810 where he was influenced by the Dutch School, notably Meindert Hobbema (1638 - 1709) and Jacob van Ruisdael (1628 - 1682).
Patrick Nasmyth sketched outdoors along the Thames and in Sussex, Hampshire and the Isle of Wight. Despite living in London he still painted Scottish scenes. A founder member of the Society of British Artists, he exhibited at the Royal Academy and the Royal Institution. He also exhibited occasionally in Edinburgh. Although not as successful as his father, Patrick Nasmyth's work appealed to nineteenth-century collectors.